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An appetite-regulating peptide that is the N-terminal portion (VPDPR) of procolipase, generated when it is cleaved to colipase. Enterostatin alters 5-HT release in the brain, and 5-HT1B receptor antagonists block the anorectic response to enterostatin. Experimentally it has been shown to suppress fat intake after peripheral and central administration. Release of enterostatin varies in a circadian fashion in some animals.

Subjects: Medicine and Health — Chemistry.

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