Neuroendocrine cells (Kulchitsky cells, EC cells) that produce and store the majority of the body's serotonin. Most are found in the epithelial lining of the gastrointestinal tract. Enterochromaffin-like cells synthesize and secrete histamine in response to stimulation by the hormones gastrin and pituitary adenylyl cyclase-activating peptide but do not produce serotonin. Most are located in the gastric mucosa, particularly in the acid-secreting regions of the stomach.
Subjects: Medicine and Health — Chemistry.