epithelial mesenchymal transition

Related Overviews


'epithelial mesenchymal transition' can also refer to...

epithelial mesenchymal transition

The epithelial–mesenchymal transition (EMT) phenomenon

Prognostic significance of epithelial–mesenchymal transition in malignant pleural mesothelioma,

PARP-1 regulates epithelial–mesenchymal transition (EMT) in prostate tumorigenesis

Menstrual effluent induces epithelial–mesenchymal transitions in mesothelial cells

New insights of epithelial-mesenchymal transition in cancer metastasis

Cardiac Epithelial-Mesenchymal Transition Is Blocked by Monomethylarsonous Acid (III)

Cyclosporine A induced epithelial–mesenchymal transition in human renal proximal tubular epithelial cells

Myeloma light chains induce epithelial-mesenchymal transition in human renal proximal tubule epithelial cells

Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells

Epithelial to mesenchymal transition-like and mesenchymal to epithelial transition-like processes might be involved in the pathogenesis of pelvic endometriosis†

Network biology approach to epithelial–mesenchymal transition in cancer metastasis: three stage theory

HnRNP A1 controls a splicing regulatory circuit promoting mesenchymal-to-epithelial transition

La enhances IRES-mediated translation of laminin B1 during malignant epithelial to mesenchymal transition

Epithelial–mesenchymal transition process in human embryonic stem cells cultured in feeder-free conditions

Cancer stem cells (CSCs) and epithelial-to-mesenchymal transition (EMT): Tumor cell plasticity challenges immunotherapy

Arsenic Exposure Perturbs Epithelial-Mesenchymal Cell Transition and Gene Expression In a Collagen Gel Assay

P-210Detection of epithelial-mesenchymal transition in colorectal cancer in consideration of intratumor heterogeneity

24PCombination of temozolomide and cisplatin reduces epithelial to mesenchymal transition in glioma cells


More Like This

Show all results sharing this subject:

  • Medicine and Health


Show Summary Details

Quick Reference

A developmental process in which epithelial cells are apparently reprogrammed and exhibit completely different behaviour. There is reduced adhesion, increased cell mobility, and loss of E-cadherin expression. The transition in behaviour is important in mesoderm formation and neural tube formation. The process is stimulated by various growth factors such as IGF-1 and TGFβ-1 and is regulated through the Ras-MAPK and Wnt signalling pathways. Ras-MAPK activates two related transcription factors, Snail and Slug, that are transcriptional repressors of E-cadherin and their expression induces EMT. Twist, another transcription factor, has also been shown to induce EMT, and is implicated in the regulation of metastasis.

Subjects: Medicine and Health.

Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.