Overview

Eps15


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An adaptor protein involved in endocytosis and trafficking of the epidermal growth factor receptor. The EH domain (Eps15-homology domain) is a highly conserved motif of ~100 aa found in many proteins involved in regulation of the endocytic pathway. The ligand of EH domains is the tripeptide Asp-Pro-Phe (NPF).

Subjects: Medicine and Health.


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