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n. a drug that causes constriction of blood vessels and is used to relieve migraine. It is administered in combination with caffeine (in Cafergot) or cyclizine and caffeine (in Migril) by mouth or in suppositories. Common side-effects are nausea and vomiting, and ergotism may develop as a result of high doses; because of this it has largely been superseded by *5HT1 agonists.

Subjects: Medicine and Health.

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