Overview

error-prone repair


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A process first demonstrated in E. coli exposed to UV light that allows DNA replication to occur across thymine dimers (q.v.), but at the cost of fidelity of replication. The resulting strand often has incorrect nucleotides inserted opposite the UV photoproducts in the template. See Chronology, 1967, Witkin; SOS response.

Subjects: Chemistry — Genetics and Genomics.


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