excitation-contraction coupling

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The sequence of events that couples electrical excitation of a muscle by the arrival of a nervous impulse at the motor end plate to the contractile process, the sliding of the filaments of the sarcomere. The coupling is brought about by the release of calcium from the sarcoplasmic reticulum, and the analogy is often drawn between this and stimulus-secretion coupling, in which calcium release into the cytoplasm is also involved.

Subjects: Medicine and Health.

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