factor C

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An endotoxin-sensitive, intracellular serine peptidase zymogen (994 aa) which initiates the coagulation cascade in the haemolymph of horseshoe crabs Limulus polyphemus and Carcinoscorpius rotundicauda. It binds endotoxin and is heterodimeric with an 80-kDa heavy chain with several sushi domains and a 52-kDa light chain.

Subjects: Medicine and Health.

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