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feline sarcoma oncogene homologue


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(fgr)

The homologue of the cytoplasmic tyrosine kinase found in Gardner–Rasheed feline sarcoma virus. The gene is activated when B cells are infected by the Epstein–Barr virus. Fgr is involved in integrin signalling in myeloid leucocytes and will increase phosphorylation of the p85 subunit of PI3 kinase.

Subjects: Medicine and Health.


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