Overview

fibrillin


'fibrillin' can also refer to...

fibrillin

fibrillin

fibrillin

fibrillin

fibrillin

Genetic and gene expression analyses of the polycystic ovary syndrome candidate gene fibrillin-3 and other fibrillin family members in human ovaries

Dermal tissue and cellular expression of fibrillin-1 in diffuse cutaneous systemic sclerosis

Mechanical assessment of elastin integrity in fibrillin-1-deficient carotid arteries: implications for Marfan syndrome

Localization of fibrillin-1 in human endometrium and decidua during the menstrual cycle and pregnancy.

Mutation of the gene encoding fibrillin-2 results in syndactyly in mice

Structure of the Mutant Fibrillin-1 Gene in the Tight Skin (TSK) Mouse

NMR analysis of cbEGF domains gives new insights into the structural consequences of a P1148A substitution in fibrillin-1.

Increased expression of latent TGF-ß binding protein-1 and fibrillin-1 in human uterine leiomyomata

Expression of latent TGF-beta binding proteins and association with TGF-beta1 and fibrillin-1 following arterial injury

Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

Inhibition of Fibrillin 1 Expression Using U1 snRNA as a Vehicle for the Presentation of Antisense Targeting Sequence

Defective secretion of recombinant fragments of fibrillin-1: implications of protein misfolding for the pathogenesis of Marfan syndrome and related disorders

Mutant Fibrillin-1 Monomers Lacking EGF-Like Domains Disrupt Microfibril Assembly and Cause Severe Marfan Syndrome

Delivery of a Hammerhead Ribozyme Specifically Down-Regulates the Production of Fibrillin-1 by Cultured Dermal Fibroblasts

 

More Like This

Show all results sharing these subjects:

  • Genetics and Genomics
  • Medicine and Health

GO

Show Summary Details

Quick Reference

A 2,871 amino acid glycoprotein associated with microfibrils about 10 nanometers in diameter. The protein is found in skin, tendon, bone, muscle, lung, kidney, blood vessels, and the suspensory ligament of the lens. Fibrillin contains 49 EGF domains. The protein is encoded by a gene symbolized by FBN1, and mutations in it are responsible for an inherited disease called Marfan syndrome (q.v.). See epidermal growth factor.

Subjects: Genetics and Genomics — Medicine and Health.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.