fibrous dysplasia

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A developmental abnormality in which changes occur in bony tissue. Trabecular bone is replaced by fibrous tissue, resulting in aching and a tendency to pathological fracture. In monostotic fibrous dysplasia one bone is affected; polyostotic fibrous dysplasia involves many bones. There is a small risk (5–10%) of malignant transformation (fibrosarcoma).

Subjects: Plastic and Reconstructive Surgery.

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