fibrous plaque

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A thickening of the wall of an artery as a result of the accumulation of smooth muscle cells and fibrous tissue in the intima. The cells often have many fat globules (foam cells) and there may be extracellular lipid; fatty streaks may be precursors. If there is necrosis the thickening may be considered an atheroma. In extreme cases the lumen of the vessel may become occluded.

Subjects: Medicine and Health.

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