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A derivative of vidarabine, an antiviral adenosine analogue, that is less susceptible to inactivation by adenosine deaminase. The active metabolite is 2-fluoro-ara-ATP which inhibits DNA polymerase α, ribonucleotide reductase and DNA primase. Used for treatment of adults with B-cell chronic lymphocytic leukaemia that has not responded to other drugs.

Subjects: Medicine and Health.

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