focal segmental glomerulosclerosis

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(FSGS) a condition in which there is scarring in some (focal) glomeruli that affects only part (segmental) of the glomerular capillary tuft. Primary FSGS overlaps with minimal change nephropathy and typically presents with the nephrotic syndrome. Secondary FSGS has a wide range of causes, from viral infections, including HIV, to haemodynamic changes associated with reduced renal mass, hypertension, and obesity, and is usually associated with less severe proteinuria.

Subjects: Medicine and Health.

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