Overview

folinic acid


'folinic acid' can also refer to...

folinic acid

folinic acid

folinic acid

folinic acid

folinic acid

folinic acid n.

folinic acid n.

folinic acid n.

Anaphylactic shock secondary to intravenous administration of folinic acid: a first report

Biweekly Irinotecan Plus Bolus 5-Fluorouracil and Folinic Acid in Patients with Advanced Stage Colorectal Cancer

Folinic Acid Supplements to Pyrimethamine-Sulfadiazine for Toxoplasma Encephalitis Are Associated with Better Outcome

Critical factors for optimizing the 5-fluorouracil-folinic acid association in cancer chemotherapy

Effects of folinic acid on forearm blood flow in patients with end-stage renal disease

Homocysteine and lipid peroxidation in haemodialysis: role of folinic acid and vitamin E

Randomised Phase III study of biweekly 24-h infusion of high-dose 5FU with folinic acid and oxaliplatin versus monthly plus 5-FU/folinic acid in first-line treatment of advanced colorectal cancer

Randomized trial on adjuvant treatment with FOLFIRI followed by docetaxel and cisplatin versus 5-fluorouracil and folinic acid for radically resected gastric cancer

A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer

A phase I study of oral uracil–ftorafur plus folinic acid in combination with weekly paclitaxel in patients with solid tumors

Neoadjuvant treatment of unresectable liver disease with irinotecan and 5-fluorouracil plus folinic acid in colorectal cancer patients

 

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A derivative of folic acid involved in purine synthesis. Administered by mouth or by injection or infusion in the form of its calcium or disodium salts, it is used to reverse the biological effects of methotrexate and other dihydrofolate reductase inhibitors and so to prevent excessive toxicity. This action is termed folinic acid rescue. Folinic acid has a potentiating effect with fluorouracil, with which it is often used. Trade names: Isovorin, Refolinon, Sodiofolin.

Subjects: Medicine and Health — Chemistry.


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