Overview

fragilysin


Show Summary Details

Quick Reference

Zinc metallopeptidase (EC 3.4.24.74, 405 aa) of the M10 family that may be a virulence factor of some strains of Bacteroides fragilis. The enzyme damages intestinal epithelium by cleaving E-cadherin and causes diarrhoea, but the correlation between fragilysin production and pathogenicity is weak.

Subjects: Medicine and Health.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.