functional cloning

'functional cloning' can also refer to...

functional cloning

functional cloning

functional cloning

functional cloning

Molecular Cloning and Functional Analysis of Sialyltransferases

Cloning, Tissue Distribution, and Functional Characterization of Chicken Glucagon Receptor

Molecular cloning and functional characterization of guinea pig IL-12

Cloning and functional characterization of carotenoid cleavage dioxygenase 4 genes

Molecular cloning and functional expression of a novel extracellular lipase from the thermotolerant yeast Candida thermophila

Cloning and characterization of a haloarchaeal heat shock protein 70 functionally expressed in Escherichia coli

Cloning and functional characterization of the ambler Class C β-lactamase of Yersinia ruckeri

Molecular cloning and functional characterisation of a glucose transporter, CaHGT1, of Candida albicans

Cloning, expression, and functional characterization of the Mycobacterium tuberculosis secA gene

Cloning, functional expression and partial characterization of the glucose kinase from Renibacterium salmoninarum


Purification, Cloning and Functional Characterization of an Endogenous beta-Glucuronidase in Arabidopsis thaliana

FANTOM DB: database of Functional Annotation of RIKEN Mouse cDNA Clones

Molecular Cloning and Functional Analysis of a Schizosaccharomyces Pombe Homologue of Escherichia Coli Endonuclease III

The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells


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In human genetics, the identification of the gene responsible for a disease from a knowledge of the underlying molecular defect. If the protein encoded by the gene is known, it is often possible to isolate the appropriate mRNAs and to use them, or cDNAs derived from them, as probes for the gene. This was the first method used successfully to clone genes responsible for certain hereditary diseases, such as sickle cell anemia, Tay-Sachs disease, and phenylketonuria. Contrast with positional cloning. See cDNA, hereditary disease, mRNA, probe.

Subjects: Chemistry.

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