'GAL4' can also refer to...





Mitochondrial dysfunction enhances Gal4-dependent transcription

The binary response of the GAL/MEL genetic switch of Saccharomyces cerevisiae is critically dependent on Gal80p–Gal4p interaction

A novel pentaglycosylceramide in ostrich liver, IV4-β-Gal-nLc4Cer, with terminal Gal(β1–4)Gal, a xenoepitope recognized by human natural antibodies

Differential expression and enzymatic properties of GalNAc-4-sulfotransferase-1 and GalNAc-4-sulfotransferase-2

Truncation of Gal4p explains the inactivation of the GAL/MEL regulon in both Saccharomyces bayanus and some Saccharomyces cerevisiae wine strains

Characterization of the Saccharomyces cerevisiae galactose mutarotase/UDP-galactose 4-epimerase protein, Gal10p

Characterization of mammalian UDP-GalNAc:glucuronide α1-4-N-acetylgalactosaminyltransferase

GAL4 GFP enhancer trap lines for analysis of stomatal guard cell development and gene expression

GAL4-GFP enhancer trap lines for genetic manipulation of lateral root development in Arabidopsis thaliana

Binding of the glucose-dependent Mig1p repressor to the GAL1 and GAL4 promoters in vivo: Regulation by glucose and chromatin structure

Receptor Specificities of Variant Gal(α1–4)Gal-Binding PapG Adhesins of Uropathogenic Escherichia coli as Assessed by Hemagglutination Phenotypes

Clonal Distribution of the Three Alleles of the Gal(α1–4)Gal-Specific Adhesin Gene papG among Escherichia coli Strains from Patients with Bacteremia

Molecular characterization and immunohistochemical localization of IV4GalNAcGgOse4Cer: a naturally occurring novel neutral glycosphingolipid in bovine brain

Discovery of Disseminated J96-like Strains of Uropathogenic Escherichia coli O4:H5 Containing Genes for Both PapGJ96 (Class I) and PrsGJ96 (Class III) Gal(α1-4)Gal-Binding Adhesins

Cloning and characterization of a novel α-galactosidase from Bifidobacterium breve 203 capable of synthesizing Gal-α-1,4 linkage


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A transcriptional activator protein encoded by the gal4 gene of yeast and required for the expression of genes encoding galactose-metabolizing enzymes. The GAL4 protein consists of two separable but essential domains (q.v.): an N-terminal (q.v.) domain which binds to specific DNA sequences upstream (q.v.) from the various target genes, and a C-terminal (q.v.) domain which is required to activate transcription. These properties of GAL4 have been exploited to develop the yeast two-hybrid system (q.v.) for detecting protein-protein interactions and the Drosophila targeted gene expression technique (q.v.) for studying the functioning of master control genes in various targeted tissues. See Chronology, 1989, Field and Song; 1995, Halder et al.

Subjects: Genetics and Genomics.

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