A tetrameric glycoprotein (EC 220.127.116.11) composed of identical 651 aa subunits that is involved in the degradation of glucuronic acid-containing glycosaminoglycans. Often used as a reporter gene. Mutations in the gene lead to mucopolysaccharidosis type VII (Sly's syndrome), an autosomal recessive lysosomal storage disease. See egasyn.
Subjects: Medicine and Health.