A germicidal disinfectant used for the cold sterilization of instruments. Safer substitutes are now used in dentistry because of the risk of skin or respiratory system sensitization to both clinical personnel and patients, which can result in dermatitis, rhinitis, or asthma. It was briefly used in the 1990s as a disinfectant in primary tooth pulpotomy but its use was discontinued because of its toxicity. Heat-tolerant dental instruments should be sterilized by autoclaving in a vacuum steam sterilizer using a validated process, since cold sterilization is difficult to validate. Trade names: Cidex, Totacide, Asep.