glyceraldehyde-3-phosphate dehydrogenase

Related Overviews


'glyceraldehyde-3-phosphate dehydrogenase' can also refer to...


More Like This

Show all results sharing this subject:

  • Medicine and Health


Quick Reference

The enzyme (GAPDH, GAPD, G3PD, EC, 335 aa) that catalyses the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate, the three-carbon intermediate of the glycolytic pathway formed by the cleavage of fructose 1,6-bisphosphate by aldolase. GAPDH interacts with various elements of the cytoskeleton, and with the trinucleotide repeat in the huntingtin gene. A testis-specific isoform (GAPD2) has been identified. Genetic variation in members of the GAPD gene family may be risk factors in Alzheimer's disease.

Subjects: Medicine and Health.

Reference entries