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'gp41' can also refer to...


HIV-1 and its transmembrane protein gp41 bind to different Candida species modulating adhesion

Humanization strategies for an anti-idiotypic antibody mimicking HIV-1 gp41

Human Immunodeficiency Virus Type 1 gp160 and gp41 Binding to Candida albicans Selectively Enhances Candidal Virulence In Vitro

Specific Enfuvirtide-Associated Mutational Pathways in HIV-1 Gp41 Are Significantly Correlated With an Increase in CD4+ Cell Count, Despite Virological Failure

Specific mutations in HIV-1 gp41 are associated with immunological success in HIV-1-infected patients receiving enfuvirtide treatment

An engineered HIV-1 gp41 trimeric coiled coil with increased stability and anti-HIV-1 activity: implication for developing anti-HIV microbicides

Human Immunodeficiency Virus Type 1 gp41 Binds to Candida albicans via Complement C3-like Region

Vertical Transmission of Human Immunodeficiency Virus Type 1: Seroreactivity by Maternal Antibodies to the Carboxy Region of the gp41 Envelope Glycoprotein

The LLSGIV stretch of the N-terminal region of HIV-1 gp41 is critical for binding to a model peptide, T20

A Single Amino-Acid Change in a Highly Conserved Motif of gp41 Elicits HIV-1 Neutralization and Protects Against CD4 Depletion

gp41 Envelope Protein of Human Immunodeficiency Virus Induces Interleukin (IL)-10 in Monocytes, but Not in B, T, or NK Cells, Leading to Reduced IL-2 and Interferon-γ Production

Anticardiolipin Antibodies in HIV Infection Are Independently Associated with Antibodies to the Membrane Proximal External Region of gp41 and with Cell-Associated HIV DNA and Immune Activation


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An HIV envelope glycoprotein (41 kDa, 861 aa), encoded by the env gene, that promotes fusion of the virus with the plasma membrane of the host cells and is essential for infectivity. It is noncovalently bound to gp120, another envelope glycoprotein. The ectodomain has an N-terminal fusion domain that is highly hydrophobic, a membrane-spanning domain, and an endomain with a Tyr-based motif that interacts with the AP-2 clathrin adaptor protein.

Subjects: Medicine and Health.

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