A recessive gene on the third chromosome of Drosophila melanogaster symbolized by c(3)G. It was discovered in 1917 by Marie and John Gowen, who showed that crossing over was suppressed in homozygous females. Later it was observed that mutant oocytes lacked synaptonemal complexes (q.v.), and the wild-type allele was found to encode a protein component of that organelle. C(3)G and the Zip 1 gene of Saccharomyces cerevisiae are orthologs. See centromeric coupling.
Subjects: Genetics and Genomics.