The family of serine/threonine protein kinases (G-protein-receptor kinases, EC 22.214.171.124) that phosphorylate agonist-occupied G-protein-coupled receptors. GRK-1 is rhodopsin kinase; GRK-2 is β-adrenergic receptor kinase-1, BARK-1, see Ark1) and many others are known. Mutations in the gene for GRK1 cause Oguchi's disease. See arrestins.
Subjects: Chemistry — Medicine and Health.