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GRK


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GRKs

GRK

GRK [Airport Code]

Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients

P440Targeting subcellular GRK2 localization

76 Regulation of G-protein coupled receptor kinases GRK2 and GRK5 in heart transplantation candidates supported by ventricular assist devices

Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease

Lymphocyte G-protein receptor kinase (GRK)3 mRNA levels in bipolar disorder

GRK2 Levels in Umbilical Arteries of Pregnancies Complicated by Gestational Hypertension and Preeclampsia

Regulation of Target System Sensitivity in Neuroinflammation: Role of GRK2 in Chronic Pain

P501GRK2 inhibition with small peptide improves cardiac function during heart failure

P655GRK2 subcellular localization in response to radiation stress in cardiac myocytes

Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure

Scoring of predicted GRK2 phosphorylation sites in Nedd4-2

Normalization of GRK2 protein and mRNA measures in patients with depression predict response to antidepressants

Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish

P705Downregulation of vascular smooth muscle GRK2 expression promotes functional and biochemical alterations in a mouse model of hypertension

The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum

Lymphocyte GRK levels as biomarkers in heart failureThe opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

 

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The family of serine/threonine protein kinases (G-protein-receptor kinases, EC 2.7.11.16) that phosphorylate agonist-occupied G-protein-coupled receptors. GRK-1 is rhodopsin kinase; GRK-2 is β-adrenergic receptor kinase-1, BARK-1, see Ark1) and many others are known. Mutations in the gene for GRK1 cause Oguchi's disease. See arrestins.

Subjects: Chemistry — Medicine and Health.


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