haem oxygenases

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haem oxygenases

Haem, haem oxygenase and ferritin in vascular endothelial cell injury

Immunohistochemical detection of haem oxygenase in AA amyloidogenesis

Haem oxygenase (HO): an overlooked enzyme of plant metabolism and defence

270. Haem Oxygenase 1 Deficiency: A Mimicker of Childhood Vasculitis

Haem oxygenase-1—a culprit in vascular and renal damage?

A Medicago sativa haem oxygenase gene is preferentially expressed in root nodules

Haem oxygenase delays programmed cell death in wheat aleurone layers by modulation of hydrogen peroxide metabolism

Nitric oxide synthase is downregulated, while haem oxygenase is increased, in patients with septic shock

Increased expression of Leydig cell haem oxygenase-1 preserves spermatogenesis in varicocele

Disrupting the bimolecular binding of the haem-binding protein 5 (AtHBP5) to haem oxygenase 1 (HY1) leads to oxidative stress in Arabidopsis

Prenatal low-level exposure to CO alters postnatal development of hippocampal nitric oxide synthase and haem-oxygenase activities in rats

Haem oxygenase-1 is involved in salicylic acid-induced alleviation of oxidative stress due to cadmium stress in Medicago sativa

Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia

PPARδ and PGC1α act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress

Cardioprotection by hypoxia-inducible factor 1 alpha transfection in skeletal muscle is dependent on haem oxygenase activity in mice

EGb761 ameliorates the formation of foam cells by regulating the expression of SR-A and ABCA1: role of haem oxygenase-1

Expression levels of haem oxygenase-1 in the omental adipose tissue and peripheral blood mononuclear cells of women with polycystic ovary syndrome

The size of a microsatellite polymorphism of the haem oxygenase 1 gene is associated with idiopathic recurrent miscarriage


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Enzymes (HSP32, EC, of which various isoforms are known, that metabolize haem to form carbon monoxide, iron, and biliverdin. Increased haem-derived CO inhibits nitric oxide synthase and is a putative neurotransmitter. Haem oxygenase-1 (HO-1, 288 aa) is an inducible heat-shock/stress protein and regulates inflammation by attenuating adhesive interactions and cellular infiltration. HO-2 (316 aa) is constitutive and present in endothelial cells, adventitial nerves of blood vessels and neurons in autonomic ganglia. The role of HO-3 is not clearly defined.

Subjects: Chemistry — Medicine and Health.

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