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heat-shock puffs


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A unique set of chromosomal puffs induced in Drosophila larvae exposed to elevated temperatures (for example, 40 minutes at 37°C). In D. melanogaster, there are nine heat-inducible puffs. Heat shock results in the transcription of a specific set of mRNAs by the genes that form the puffs in polytene chromosomes. In culture, heat-shocked Drosophila cells also transcribe these same mRNAs into specific heat-shock proteins. See Chronology, 1962, Ritossa.

Subjects: Genetics and Genomics.


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