The gene, located at Xq27, which encodes factor 9, the plasma thromboplastin component (q.v.). HEMB is much smaller than HEMA. HEMB contains 34 kilobases of DNA and is made up of 8 exons. Most individuals suffering from hemophilia B have deletions in the factor 9 gene. The liver is the site of transcription and translation of the HEMB mRNA. See gene, hemophilia.
Subjects: Genetics and Genomics.