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'HNF' can also refer to...



Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4α and HNF1β in a pancreatic β-cell line

Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A

Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis

HNF1 β/TCF2 mutations impair transactivation potential through altered co-regulator recruitment

Computational discovery and in vivo validation of hnf4 as a regulatory gene in planarian regeneration

Human mutations affect the epigenetic/bookmarking function of HNF1B


Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors

Characterization of a Dominant Negative Mutant Form of the HNF-4 Orphan Receptor

Criteria for HNF1B analysis in patients with congenital abnormalities of kidney and urinary tract

Characterization of the PC4 Binding Domain and its Interactions with HNF4α

Renal cysts and diabetes due to a heterozygous HNF-1β gene deletion

HNF1B-MODY: A Disorder of Development With Diabetes and Congenital Malformations in the Pancreas and Urogenital Tract Due to Mutations in HNF1B

The embryonic expression of the tissue-specific transcription factor HNF1α in Xenopus: Rapid activation by HNF4 and delayed induction by mesoderm inducers

Extinction of α1-antitrypsin expression in cell hybrids is independent of HNF1α and HNF4 and involves both promoter and internal DNA sequences

Transcriptional Coactivators CBP and p300 Cooperatively Enhance HNF-1α–Mediated Expression of the Albumin Gene in Hepatocytes

Mutations in the RARE and MARE regulatory sequences of HNF1β are not a frequent cause of kidney/urinary tract malformation


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A family of transcription factors (hepatocyte nuclear factors) enriched in liver. HNF1 is predominantly expressed in liver and kidney and selectively interacts with the control regions of several liver-specific genes. Heterozygous mutations in hepatocyte nuclear factor (HNF)-1α and HNF-1β result in maturity-onset diabetes of the young.

Subjects: Chemistry.

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