high endothelial venule

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'high endothelial venule' can also refer to...

high endothelial venule

Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules

Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling

Characterization of mac25/angiomodulin expression by high endothelial venule cells in lymphoid tissues and its identification as an inducible marker for activated endothelial cells

P-selectin glycoprotein ligand-1 mediates L-selectin-independent leukocyte rolling in high endothelial venules of peripheral lymph nodes

Plasmacytoid dendritic cells employ multiple cell adhesion molecules sequentially to interact with high endothelial venule cells – molecular basis of their trafficking to lymph nodes

KSGal6ST generates galactose-6-O-sulfate in high endothelial venules but does not contribute to L-selectin-dependent lymphocyte homing

Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes

Rapid immunosurveillance by recirculating lymphocytes in the rat intestine: critical role of unsulfated sialyl-Lewis X on high endothelial venules of the Peyer’s patches

Roles of α4 integrins/VCAM-1 and LFA-1/ICAM-1 in the binding and transendothelial migration of T lymphocytes and T lymphoblasts across high endothelial venules

A high endothelial venule‐expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions


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A type of venule in which the endothelium, instead of being thin and squamous in morphology, is cuboidal. They are characteristic of lymph nodes where lymphocyte extravasation occurs in the normal trafficking. Morphologically similar endothelium is associated with some chronic inflammatory lesions. The adhesion molecules, GlyCAM-1 (MadCAM-1 in mucosal HEVs), ICAM-1, and CD34 expressed on the apical surfaces account for preferential lymphocyte adhesion through selectins and LFA-1.

Subjects: Medicine and Health.

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