high-mobility group proteins

'high-mobility group proteins' can also refer to...

high mobility group proteins

high-mobility group proteins

Role of the high mobility group A* proteins in human lipomas

Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis

Evolution of High Mobility Group Nucleosome-Binding Proteins and Its Implications for Vertebrate Chromatin Specialization

The role of high mobility group box chromosomal protein 1 in rheumatoid arthritis

High mobility group proteins 1 and 2 recognize chromium-damaged DNA.

High-mobility group box 1 protein (HMGB1) in ischaemic heart disease: beneficial or deleterious?

Calf thymus high mobility group proteins are nonenzymatically glycated but not significantly glycosylated

Characterization of Transgenic Arabidopsis Plants Overexpressing High Mobility Group B Proteins under High Salinity, Drought or Cold Stress

A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

C-terminal extension of calmodulin-like 3 protein from Oryza sativa L.: interaction with a high mobility group target protein

High Mobility Group Proteins 1 and 2 Can Function as DNA-Binding Regulatory Components for DNA-Dependent Protein Kinase In Vitro

Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation

The Epstein–Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins

Single-molecule kinetics reveal microscopic mechanism by which High-Mobility Group B proteins alter DNA flexibility

The role of intercalating residues in chromosomal high‐mobility‐group protein DNA binding, bending and specificity

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors


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A set of nonhistone chromosomal proteins involved in a wide variety of cellular processes including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the induction of neoplastic transformation and metastatic progression. Contain conserved DNA-binding peptide motifs (AT hooks) that preferentially bind to the minor groove of many AT-rich promoter and enhancer DNA regulatory elements. Lack of HMGA1 (215 aa) is reported to cause insulin resistance and diabetes; HMGIY has been suggested as a potential oncogene. HMG2 (208 aa) is a component of the SET complex.

Subjects: Medicine and Health.

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