An allele at the albino locus (with known examples in the mouse, rat, rabbit, guinea pig, hamster, and cat) associated with a very lightly pigmented body and somewhat darker extremities. The form of tyrosinase encoded by this gene is temperature sensitive and normally functions well only in the extremities where the body temperature is lower. Such animals raised in cold environments show darker pigmentation. See albinism, temperature-sensitive mutation, tyrosinase.
Subjects: Genetics and Genomics.