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histamine receptor


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Receptors for histamine fall into two main classes, H1 and H2; the former are mostly in skin, nose, and airways and are targeted by antihistamine drugs (e.g. fexofenadine, mepyramine) that are used for allergic responses. H2-blockers are antagonists of the H2 receptors that reduce gastric acid secretion and are used in treatment of gastric and duodenal ulcers. Examples are cimetidine (Tagamet), famotidine (Pepcid), and ranitidine (Zantac).

Subjects: Chemistry.


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