histone acetylation

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'histone acetylation' can also refer to...

histone acetylation

Histone acetylation in gene regulation

Histone acetylation-independent transcription stimulation by a histone chaperone

RNA-dependent dynamic histone acetylation regulates MCL1 alternative splicing

Roles of histone acetylation in the Dnmtl gene expression

The role of histone acetylation in SMN gene expression

Histone acetylation and transcriptional regulation in the genome of Saccharomyces cerevisiae

Reversible Histone Acetylation Involved in Transcriptional Regulation of WT1 Gene

A Decade of Histone Acetylation: Marking Eukaryotic Chromosomes with Specific Codes

Curcumin ameliorates nephrosclerosis via suppression of histone acetylation independent of hypertension

Sequence specific transcription factor, JDP2 interacts with histone and inhibits p300-mediated histone acetylation

Gene-Selective Histone H3 Acetylation in the Absence of Increase in Global Histone Acetylation in Liver of Rats Chronically Fed Alcohol

Diallyl disulfide increases histone acetylation in colon cells in vitro and in vivo

Coordinated allele-specific histone acetylation at the differentially methylated regions of imprinted genes

Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition

Histone H3 tail acetylation modulates ATP-dependent remodeling through multiple mechanisms

Replication-independent nucleosome exchange is enhanced by local and specific acetylation of histone H4

Changes in histone H4 acetylation during in vivo versus in vitro maturation of equine oocytes

Misregulation of histone acetylation in Sertoli cell‐only syndrome and testicular cancer


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The post-translational modification of histones by histone acetyl transferases (HATs; EC 2.3.1.-) which add acetyl groups to N-terminal lysine residues. Acetylation reduces the binding affinity between histones and DNA, facilitating transcription by making it easier for RNA polymerase and transcription factors to access the promoter region. Acetylation of histone H4 is considered to be important in replication-dependent nucleosome assembly. Deacetylation (by histone deacetylases (HDACs) has the opposite effect.

Subjects: Medicine and Health.

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