histone genes

'histone genes' can also refer to...

histone genes

histone genes

Histone acetylation in gene regulation

Reversible Histone Acetylation Involved in Transcriptional Regulation of WT1 Gene

Dynamic and distinct histone modifications of osteogenic genes during osteogenic differentiation

The role of histone acetylation in SMN gene expression

Kluyveromyces lactis genome harbours a functional linker histone encoding gene

Roles of histone acetylation in the Dnmtl gene expression

Effect of histone methyltransferase gene mutations on sporulation in S. cerevisiae

Cloning and Characterization of the Major Histone H2A Genes Completes the Cloning and Sequencing of Known Histone Genes of Tetrahymena Thermophila

Organization of the Chicken Histone Genes in a Major Gene Cluster and Generation of an Almost Complete Set of the Core Histone Protein Sequences

Gene-Selective Histone H3 Acetylation in the Absence of Increase in Global Histone Acetylation in Liver of Rats Chronically Fed Alcohol

FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors

Characterization of combinatorial histone modifications on lineage-affiliated genes during hematopoietic stem cell myeloid commitment

Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

Several highly divergent histone H3 genes are present in the hypotrichous ciliate Stylonychia lemnae

Simple histone acetylation plays a complex role in the regulation of gene expression

Histone acetyltransferase p300 promotes MKL1-mediated transactivation of catechol-O-methyltransferase gene


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In both the sea urchin and Drosophila, these genes are repetitive and clustered. In Strongylocentrotus purpuratus, the genes for H4, H2B, H3, H2A, and H1 lie in a linear sequence. They are transcribed from the same DNA strand to form a polycistronic message, and are separated by DNA spacers of similar lengths. In Drosophila there are about 110 copies of the histone genes, and these are localized in a four-band region in the left arm of chromosome 2. The gene sequence is H3, H4, H2A, H2B, H1. Two genes are transcribed from one DNA strand, three from the other. The gene order in Xenopus laevis is the same as in Drosophila. In humans, histone genes show less clustering, and they are located on a variety of chromosomes (1, 6, 12, and 22). Notophthalmus viridescens (q.v.) has 600 to 800 copies of the histone gene repeat. Transcribing histone genes have been detected in loops at specific loci on lampbrush chromosomes 2 and 6. Most histone genes lack introns (q.v.). See Chronology, 1972, Pardue et al.; 1981, Gall et al.; Strongylocentrotus purpuratus.

Subjects: Genetics and Genomics.

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