Disorders in which there is under- or overproduction of a hormone which then affects systems regulated by the hormone in question, including, in some cases, the production of other hormones. In some cases the deficiency can arise because of a failure to process a prohormone; in other cases the defect may be in the receptor (as in androgen insensitivity syndrome, Reifenstein's syndrome). Other examples include acromegaly; Addison's disease; some types of chondrodysplasia; Cushing's syndrome; diabetes; dystrophia adiposogenitalis; giantism; hyperadrenalism; hyperparathyroidism; hyperthyroidism; hypogonadism; hypoparathyroidism; hypopituitarism; hypothyroidism; Laron's syndrome; lipoid congenital adrenal hyperplasia; nesidioblast (nesidioblastosis); triple A syndrome. Albright hereditary osteodystrophy, McCune–Albright syndrome, and pseudohypoparathyroidism are caused by mutations in genes for granins. Some disorders are described in the entries for the hormone involved: see angiotensin; antiMüllerian hormone; atrial natriuretic peptide; erythropoietin; glucocorticoids; gonadotropin-releasing hormone; growth hormone; kisspeptins; melanin-concentrating hormone; melanocortin; melanocyte-stimulating hormone; thymopoietin; vasopressin.
Subjects: Medicine and Health.