Overview

hormone-sensitive lipase


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An enzyme (EC 3.1.1.79, 1076 aa) that converts stored triglyceride into free fatty acids, the rate-limiting step in mobilizing energy from the adipocyte store. The enzyme is controlled hormonally (insulin stimulates dephosphorylation and inhibition) and neuronally (catecholamines stimulate).

Subjects: Medicine and Health — Chemistry.


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