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hu-li tai shao (hts)


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A second chromosomal gene in Drosophila melanogaster which encodes isoforms of adducin-related protein. Some are expressed during pre-adult development (e.g., in the embryonic central nervous system and epidermis and in the digestive system of embryos and larvae). Two isoforms are expressed in the germ line. One localizes in the spectrosome (q.v.) and the fusome (q.v.) and is homologous to mammalian adducin (q.v.), while the other coats ring canals (q.v.). Female sterile mutations of hts eliminate the formation of spectrosomes and fusomes, and produce egg chambers with reduced numbers of nurse cells, which often lack oocytes (hence the name hu-li tai shao, which means too little nursing in Chinese). See cystocyte divisions.

Subjects: Genetics and Genomics.


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