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hybrid cell


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Any cell, other than a zygote, that contains elements from two or more genomes, usually as a result of cell fusion to produce a heterokaryon. The production of hybrid cells is an essential step in generating monoclonal antibodies. Cybrid (cytoplasmic hybrid) cells are formed by the transfer of a nucleus from one species into the enucleated cytoplasm of an egg from another species, which of course retains its mitochondria.

Subjects: Medicine and Health.


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