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Icelandic-type cerebroarterial amyloidosis


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An autosomal dominant form of cerebral amyloid angiopathy (amyloidosis VI). Symptoms often begin at age 30–40 with multiple brain haemorrhages (mostly in the basal ganglia), dementia, paralysis (weakness), and death in 10–20 years. Caused by mutation in the gene encoding cystatin C.

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