Overview

idiotope


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The antigenic determinants (epitopes) that are unique to a particular immunoglobulin, one that is directed against a particular antigen and is produced by a clone of cells, or unique to a T-cell receptor. Each immunoglobulin or receptor may have multiple idiotopes which collectively constitute the idiotype. The idiotope is often the antigen-binding site and located in the variable region of the immunoglobulin product of that clone.

Subjects: Medicine and Health — Chemistry.


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