Overview

immunodominance


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Within a complex immunogenic molecule, the ability of a specific component (1) to elicit the highest titer of antibodies during an immune response, or (2) to bind more antibodies from a given polyvalent antiserum than any other component of that same molecule. For example, in a glycoprotein antigen, a specific monosaccharide may be the most highly antigenic component of the entire molecule and therefore exhibits immunodominance over other components of the same molecule.

Subjects: Genetics and Genomics — Chemistry.


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