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The regulation of the immune system, particularly the cellular and molecular mechanisms of activation, proliferation, and differentiation of human T and B cells. A complex set of feedback controls involving cell–cell interactions and through cytokines regulates the nature of the response that is elicited by antigenic challenge. There is also regulation as antigen is eliminated and, according to the immunological network theory, through the formation of anti-idiotype antibodies.

Subjects: Medicine and Health.

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