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indirubin-3′-monoxime


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A selective inhibitor of cyclin-dependent kinases (CDKs) that arrests cells in the G2/M phase of the cell cycle. Also inhibits glycogen synthase kinase and tau phosphorylation in vitro and in vivo at Alzheimer's disease-specific sites. It is the active ingredient of Danggui Longhui Wan, a herbal mixture used in traditional Chinese medicine.

Subjects: Medicine and Health.


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