intergenic spacer

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The region between ribosomal genes in eukaryotes and prokaryotes, commonly used in genotyping studies. In eukaryotes the IGS region varies in length from about 2 kb in yeast to 21 kb in mammals, and is highly variable, even among individuals of the same species. Variation is due to different numbers of internal subrepeats, some of which are duplications of the core promoter which enhances rDNA transcription.

Subjects: Medicine and Health.

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