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interleukin-12


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'interleukin-12' can also refer to...

interleukin 12

interleukin-12

Interleukin-12 and Interleukin-27 Regulate Macrophage Control of Mycobacterium tuberculosis

Interleukin 12 (IL12B), interleukin 12 receptor (IL12RB1) and interleukin 23 (IL23A) gene polymorphism in systemic lupus erythematosus

In situ expression of interleukin-10 and interleukin-12 in active human cutaneous leishmaniasis

Early Production of γ-Interferon in Clinical Malaria: Role of Interleukin-18 and Interleukin-12

Inherited Disorders of the Interleukin-12–Interleukin-23/Interferon-γ Circuit

Role of interleukin-12 in patients with dengue hemorrhagic fever

Interleukin-12b Polymorphisms in Association With Susceptibility to Severe Sepsis

Recurrent Salmonella Bacteremia in Interleukin-12 Receptor β1 Deficiency

Biliary Cirrhosis in a Child with Inherited Interleukin-12 Deficiency

Interleukin-12 Receptor β1 Deficiency Presenting as Recurrent Salmonella Infection

Interleukin-12 Receptor β1 Deficiency Predisposing to Disseminated Coccidioidomycosis

Natural Measles Causes Prolonged Suppression of Interleukin-12 Production

Intranasal Interleukin-12 is a Powerful Adjuvant for Protective Mucosal Immunity

Interleukin-12 Regulates the Response to Chemotherapy in Experimental Visceral Leishmaniasis

Endogenous Interleukin-12 Regulates Acquired Resistance in Experimental Visceral Leishmaniasis

Evidence for interleukin-1-independent stimulation of interleukin-12 and down-regulation by interleukin-10 in Helicobacter pylori-infected murine dendritic cells deficient in the interleukin-1 receptor

Antitumor Efficacy of Adenocarcinoma Cells Engineered to Produce Interleukin 12 (IL-12) or Other Cytokines Compared With Exogenous IL-12

 

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(IL-12)

A heterodimeric cytokine (NK stimulatory factor; cytotoxic lymphocyte maturation factor, IL12/p70, 219 aa and 328 aa) that promotes Th1 responses and regulates immunoglobulin isotype selection. The heterodimeric receptor (662 and 862 aa) activates the JAK–STAT pathway. High levels have been implicated in autoimmune disorders.

Subjects: Chemistry.


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