'interleukin-18' can also refer to...


Interleukin-18 and Host Defense against Infection

Production of Interleukin-18 in Human Tuberculosis

Role of Interleukin (IL)-18 in experimental paracoccidioidomycosis

Effects of Megestrol Acetate on Circulating Interleukin-15 and Interleukin-18 Concentrations in Healthy Elderly Men

Early Production of γ-Interferon in Clinical Malaria: Role of Interleukin-18 and Interleukin-12

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice

Involvement of interleukin-18 in severe Plasmodium falciparum malaria

Role of Interleukin-18 in Human Immunodeficiency Virus Type 1 Infection

Interleukin-18: a potent pro-inflammatory cytokine in atherosclerosis EXPERT'S PERSPECTIVE

Cloning and Characterization of a New Isoform of Mouse Interleukin-18

Recombinant Interleukin-18 Protects against Disseminated Candida albicans Infection in Mice

Interleukin-18 is a strong predictor of hospitalization in haemodialysis patients

Macrophage-derived interleukin-18 in experimental renal allograft rejection

Evidence for the expression of interleukin (IL)-18, IL-18 receptor and IL-18 binding protein in the human endometrium

Human Host Defense and Cytokines in Mycobacterial Infectious Diseases: Interleukin-18 Cannot Compensate for Genetic Defects in the Interleukin-12 System

Elevated levels of interleukin-13 and IL-18 in patients with dengue hemorrhagic fever

Interleukin-18 expression by alveolar epithelial cells type II in tuberculosis and sarcoidosis

Reduced host resistance and Th1 response to Cryptococcus neoformans in interleukin-18 deficient mice


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A pro-inflammatory cytokine (interferon-γ inducing factor, IGIF, IIF) of the IL-1 family, that induces interferon-γ production from T cells, augments T-cell proliferation and NK activity in cultures of human peripheral blood mononuclear cells, and has a role in angiogenesis. The precursor is processed by caspase-1 to produce the mature protein (157 aa). The receptor (541 aa) activates NFκB.

Subjects: Medicine and Health.

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