Show Summary Details

Quick Reference


A cytokine of the IL-10 family (IL-10-related T-cell-derived inducible factor, IL-TIF, 179 aa), produced by activated T cells. Binding to the receptor, which shares a common subunit with the IL-10 receptor, activates the STAT pathway. It has been suggested that IL-22, together with IL-17, mediates crosstalk between the immune system and epithelial cells and is involved in host defence against extracellular pathogens at mucosal sites.

Subjects: Medicine and Health.

Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.