interleukin 3

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A cytokine (HCGF, MCGF, multi-SCF, 140 aa) produced by mitogen-activated T cells that is a haematopoietic colony-stimulating factor (HCGF) and has neurotrophic activity. It is species specific—the human form is ineffective in mouse systems and vice versa. The receptor is a heterodimer with a ligand-specific α chain (378 aa) and a β chain (897 aa) in common with the receptors for IL-5 and GM-CSF.

Subjects: Medicine and Health — Chemistry.

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