Overview

interleukin-1 converting enzyme


Show Summary Details

Quick Reference

(ICE)

A cytoplasmic cysteine endopeptidase (caspase-1, EC 3.4.22.36, 404 aa) that cleaves pro-IL-1β (269 aa) into mature IL-1β (153 aa) prior to release. The ICE gene has some homology with the ced-9 gene of Caenorhabditis elegans that encodes a caspase involved in apoptosis.

Subjects: Medicine and Health.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.