interleukin-1 converting enzyme

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A cytoplasmic cysteine endopeptidase (caspase-1, EC, 404 aa) that cleaves pro-IL-1β (269 aa) into mature IL-1β (153 aa) prior to release. The ICE gene has some homology with the ced-9 gene of Caenorhabditis elegans that encodes a caspase involved in apoptosis.

Subjects: Medicine and Health.

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