Overview

inversin


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A protein (nephrocystin-2, 1062 aa) that interacts with the anaphase-promoting complex subunit-2, has a role in primary cilia function, and is involved in the cell cycle. Mutations lead to reversal of left–right polarity (situs inversus) and cyst formation in the kidneys (nephronophthisis) but is distinct from Kartagener's syndrome.

Subjects: Medicine and Health.


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